AI Research Infrastructure: NSF announced $83M for integrated data systems and services to help researchers pair scientific data with computing and AI, aligning with the White House Genesis Mission. Genesis Mission Rollout: The Department of War is partnering with DOE’s American Science and Security Platform and plans major funding for AI-enabled discovery workflows, including the Digital Biosecurity Forge with Lawrence Livermore. Space-Based Compute Push: SpaceX and xAI say they’re building an 11-million-square-foot satellite factory in Texas to move AI computing into orbit via orbital data centers. PFAS Fight: Wisconsin DOJ joined a coalition opposing an EPA rollback that would reduce federal requirements to test, report, and treat “forever chemicals” in drinking water. Arizona Tech & Semiconductors: TSMC expanded its Arizona build-out to $265B, adding more advanced fabs and packaging aimed at AI chip demand; local aerospace supplier AIRO Group’s Phoenix facility earned AS9100D certification. Water Crisis in the Southwest: Lake Powell continues shrinking, forcing marinas and boat ramps to adapt as the Colorado River basin hits record lows. Public Health: FDA issued an 11th emergency authorization for ivermectin in horses to prevent New World screwworm infestations. Arizona Science Spotlight: ASU professor Jay Famiglietti won a UN water prize for using NASA GRACE satellites to map groundwater depletion.